Spegra Tablet contains three active ingredients: Dolutegravir 50 mg, Emtricitabine 200 mg, and Tenofovir Alafenamide 25 mg. All three are delivered in a single solid tablet. The product is made by Emcure Pharmaceuticals and is available for bulk ordering through Get HIV Treatment.
Uses
Spegra Tablet is used to treat Human Immunodeficiency Virus type 1 infection in adults. It works for both treatment-naive patients and those who have been on prior therapy. The combination targets the virus at three separate points in its replication cycle. Demand for this single-tablet format is consistent among resellers in markets where one-tablet regimens are the standard of care.
How It Works
Each of the three active ingredients targets a different stage of HIV replication. Dolutegravir blocks the integrase enzyme. Without this enzyme, the virus cannot insert its genetic material into the host cell’s DNA and cannot establish a permanent infection.
Emtricitabine belongs to the nucleoside reverse transcriptase inhibitor class. It mimics a natural DNA building block. Once incorporated into the viral chain, it stops that chain from growing any further.
Tenofovir Alafenamide belongs to the same drug class. After absorption, the body converts it into Tenofovir diphosphate. This then competes with the building blocks the virus needs to copy its genetic material. Three mechanisms. One tablet.
Available Strengths and Pack Sizes
Spegra Tablet is available in the following fixed combination:
- Dolutegravir 50 mg + Emtricitabine 200 mg + Tenofovir Alafenamide 25 mg
This is a single-strength product. The 50 mg / 200 mg / 25 mg configuration is the only available variant.
Pack size and strip details are available on request through Get HIV Treatment. Buyers placing bulk orders can confirm current pack formats at the time of ordering.
Side Effect
The side effects of Spegra Tablet are typical of integrase inhibitor and nucleoside reverse transcriptase inhibitor combinations. Dolutegravir is associated with headache, insomnia, and nausea. Emtricitabine and Tenofovir Alafenamide are associated with diarrhea, fatigue, and nausea.
Tenofovir Alafenamide has a lower impact on kidney function and bone density compared to older Tenofovir formulations. This is a relevant factor for buyers comparing it against earlier generation combinations. Liver enzyme changes have also been noted with this drug class.
Shelf Life, Storage, and Packaging
Store Spegra Tablet below 30 degrees Celsius in a dry place away from direct light. The tablets are sensitive to moisture. Packaging should stay sealed until point of use.
Standard shelf life for this class of product is typically 24 months from the manufacturing date. Buyers should confirm the batch expiry at the time of ordering to plan stock rotation. The solid tablet format holds up well during long-distance shipping when kept within the recommended temperature range.
Pricing at Get HIV Treatment
Get HIV Treatment carries Spegra Tablet at competitive pricing for resellers and stockists. Current per-strip and bulk order rates are available directly through the platform. A three-drug combination in a single tablet also reduces per-unit handling costs compared to sourcing the three compounds separately. Volume tiers are available for buyers placing consistent repeat orders.
Why Buyers Choose This Product
The fixed-dose format reduces supply chain complexity for resellers stocking HIV treatment lines. Demand for this combination is stable in markets where integrase inhibitor-based regimens are the preferred treatment standard. Emcure Pharmaceuticals Limited has an established manufacturing record in antiretroviral production. The product supports reliable reorder cycles and fits naturally into wholesale antiretroviral portfolios.





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